Biology lab report


RhoC is a G protein present in some cancers. RhoC is an RNA sequence that facilitates the assembly of focal adhesions and the organization of actin stress fibers. It is related to other genes within the Rho family which regulates cell motility. RhoC is commonly expressed in whole blood cells, pancreatic tissues, and breast tissues. Our null hypothesis was that RhoC suppresses and regulates cancer cells. This is very significant in order to design drugs to decrease tumor metastasis and to inhibit several mutations if it is a common mutation, as well as, for individuals with cancer affected by the mutations of RhoC. It is also important because the frequency percentage of the mutation is extremely low that allows us to conclude this is not a driver mutation. Within a cell this G protein is most commonly located on the cytoplasmic side of the cell in the cell membrane or lipid-anchor. However, in some cases RhoC can be found in the cleavage furrow if the cell is dividing. This could mean RhoC has a role in regulation during cytokinesis which makes tumors become malignant. When RhoC is overexpressed, it enhances metastasis which means this is an important regulator in tumor invasion (Clark, Golub, Lander, & Hynes, 2000). A study on breast cells found metastasis is part of what makes Inflammatory Breast Cancer so aggressive in the beginning stages. They concluded in this study that overexpression directly impacted angiogenic factors of cancer cells. Researchers found over 90% of tumor samples had overexpressed RhoC within them(Golen, Wu, Qiao, Bao, & Merajver, 2000). Since RhoC is a key regulator for cancer stem cells a study was performed to see the effects of RhoC on ovarian cancer cells. A PCR was run to observe the expression levels of RhoC along with other proteins. It was concluded that si-RhoC suppressed expression levels of the other proteins, drug resistance and invasion (Sang et al., 2016). RhoC is commonly experimented with how it can regulate specific cancer cells. Another research team studied the effects of RhoA and RhoC on prostate cancer cells. This team specifically tested its effects on glutamine metabolism that is a contributor to cell growth in prostate cancer. They concluded that RhoC overexpression did not show a specific impact to the lack of glutamine. Although the dominant negative mutation of the RhoC protein was more resistant than the overexpressed RhoC (Paiva et al., 2018)

Don't use plagiarized sources. Get Your Custom Essay on
Biology lab report
Get an essay WRITTEN FOR YOU, Plagiarism free, and by an EXPERT!
Order Essay
Homework Paper
Order NOW For A 10% Discount!
Pages (550 words)
Approximate price: -

Our Advantages

Plagiarism Free Papers

All our papers are original and written from scratch. We will email you a plagiarism report alongside your completed paper once done.

Free Revisions

All papers are submitted ahead of time. We do this to allow you time to point out any area you would need revision on, and help you for free.

Free Title-page

A title page preceeds all your paper content. Here, you put all your personal information and this we give out for free.

Free Bibliography

Without a reference/bibliography page, any academic paper is incomplete and doesnt qualify for grading. We also offer this for free.

Originality & Security

At, we take confidentiality seriously and all your personal information is stored safely and do not share it with third parties for any reasons whatsoever. Our work is original and we send plagiarism reports alongside every paper.

24/7 Customer Support

Our agents are online 24/7. Feel free to contact us through email or talk to our live agents.

Try it now!

Calculate the price of your order

We'll send you the first draft for approval by at
Total price:

How it works?

Follow these simple steps to get your paper done

Place your order

Fill in the order form and provide all details of your assignment.

Proceed with the payment

Choose the payment system that suits you most.

Receive the final file

Once your paper is ready, we will email it to you.

Our Services

We work around the clock to see best customer experience.


Flexible Pricing

Our prices are pocket friendly and you can do partial payments. When that is not enough, we have a free enquiry service.


Admission help & Client-Writer Contact

When you need to elaborate something further to your writer, we provide that button.


Paper Submission

We take deadlines seriously and our papers are submitted ahead of time. We are happy to assist you in case of any adjustments needed.


Customer Feedback

Your feedback, good or bad is of great concern to us and we take it very seriously. We are, therefore, constantly adjusting our policies to ensure best customer/writer experience.