obesity and heart disease

Specific Requirements: create a simple cohort study. Utilize posted resources with sample case, grid, and formula for calculations.

Develop a simple cohort study:

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· Describe the case scenario and concerns for designated population (you make up the scenario).

· Plot realistic numbers in grid or chart (you decide on #’s).

· Calculate numbers for relative risk showing all work as per sample posted.

· Explain the outcomes.

· What primary prevention measure could be taken to reduce risk?


Example below

A retrospective cohort study was done to assess the risk of developing mesothelioma for coal miners. The study had 5,453 men who had been exposed to the toxins in a coal mine and 4, 300 men living in the same town who had not been exposed to the toxins. Among those exposed 950 men had developed the disease. Among those not exposed 220 men developed the disease.


Disease Develops




No Mesothelioma














0.174 X 1000



Not Exposed








0.051 X 1000

51 per 1000


Incidence in exposed:


a 950 = 0.174 X 1000 = 174

a + b 5453



Incidence in Not Exposed:


c 220 = 0.051 X 100 = 0.51 X 1000 = 51

c + d 4, 300


RR: a ÷ b = 74 = 3.4

a+b b+c 51


RR: Incidence of exposed divided by incidence of non- exposed

Incidence in exposed is: 950 ÷ 5453 = 0.174 X 1000 = 174 per 1000

Incidence in non-exposed = 220 ÷ 4300 = 0.51 X 1000 = 51 per 1000

174 = 3.4



AR: Incidence in exposed – incidence in non-exposed ÷ incidence in exposed


174 – 51 = 123 ÷ 174 = 0.76 or 70.6%


70.6 % of mesothelioma for coal miners is attributed to exposure in the mines.

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